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KMID : 0360220180590090876
Journal of the Korean Ophthalmological Society
2018 Volume.59 No. 9 p.876 ~ p.880
Bilateral Frosted Branch Angiitis in Kikuchi-Fujimoto Disease
Kim Hun-Min

Choi Young-Je
Kim Seong-Taek
Abstract
Purpose: A case of frosted branch angiitis in Kikuchi-Fujimoto disease is reported.

Case summary: A 33-year-old male complained of a sudden decrease in visual acuity that developed in both eyes 5 days prior. He suffered from a headache, chills, myalgia, and flank pain 1 week before. The initial best-corrected visual acuity (BCVA) was 0.1 in the right eye and 0.2 in the left eye. On slit lamp examination, no inflammatory finding was observed in the anterior chamber and vitreous body of both eyes. On fundus examination, a diffuse vascular sheathing-like frosted branch was found in the retinal vessels, and retinal hemorrhage was observed. Fluorescein angiography showed staining and leakage of dye along the vascular sheathing. Serological findings were negative, showing no evidence of an autoimmune disease or viral infection. Neck ultrasonography revealed non-tender left cervical lymph node enlargement >1 cm in diameter. Ultrasound-guided fine needle aspiration cytology showed findings compatible with Kikuchi-Fujimoto disease, including necrotic changes and pronounced karyorrhexis, plus histiocyte and lymphocyte infiltration without neutrophils. We started systemic steroid therapy. One month after treatment, the BCVA of both eyes improved to 1.0.

Conclusions: In patients with frosted branch angiitis, systemic disease such as Kikuchi-Fujimoto disease should be considered.
KEYWORD
Frosted branch angiitis, Kikuchi-Fujimoto disease, Necrotizing lymphadenitis
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